However, its ability to inhibit the hepatic metabolism of other medications (such as clobazam and sodium valproate) has the potential to cause adverse effects. This is demonstrated by the increased rates of adverse events, serious adverse events and withdrawals in trials for childhood epilepsy syndromes but not other indications. Additional safety data from clinical trials outside of childhood epilepsy syndromes and from studies of OTC CBD products would be beneficial.
What Is THC?
Physical dependence on THC is more likely among people who use high-THC cannabis strains. Hemp oil has a higher CBD content than marijuana-derived CBD, and many CBD products contain hemp-derived CBD. Hemp seed oil comes from the Cannabis Sativa family and has long been used to make clothing, paper, and cloth for medical purposes.
- Some brands also produce CBD gummies and capsules for controlled dosing of CBD.
- The cannabis plant has hundreds of active chemicals, including more than 120 cannabinoids found in the stalks, seeds and flowers.
- It differs from its cannabinoid counterpart, THC, in that it does not produce a high or any intoxicating effects.
- In some studies, the use of Epidiolex was linked to liver problems and drug interactions.
Sources of CBD Oil and What to Look For
- A 2018 preclinical animal study examining topical administration to rats addicted to alcohol and cocaine found that CBD effectively reduced drug use in the subjects.
- Some common side effects of CBD may include dry mouth, low blood pressure, lightheadedness, and drowsiness.
- Good hemp plants contain high levels of CBD and virtually undetectable amounts of THC.
- CBD has been shown to be a safe compound in both animals and humans, which is of critical importance from a therapeutic point of view.
CBD use should be individualized and vetted by a healthcare professional, such as a pharmacist or healthcare provider. OTC CBD oil products are not intended to treat, cure, or prevent disease. Those with addiction experience several symptoms, from impaired cognition to compromised body functions, along with behaviors that negatively impact their social lives and relationships. Compared with the placebo group, subjects treated with CBD reported lower anxiety levels and cravings from heroin addiction withdrawals.
Is Cannabidiol (CBD) Addictive?
After tetrahydrocannabinol (THC), which is the most abundant compound in cannabis, CBD is the second most abundant. Other names for CBD oil include CBD-rich hemp oil, hemp-derived CBD oil, or CBD-rich cannabis oil. CBD is generally considered to be safe and has been used medicinally for decades. The suggested medicinal effects of CBD include decreasing anxiety, improving sleep, and providing other neuroprotective effects. A study noted that CBD has a positive impact on the intoxication and relapse phase of opioid addiction(11).
- For example, a 2022 comprehensive review of the effects of cannabinoids on normal sleep and sleep disorders showed that cannabis products have minimal to no effects on sleep and may produce negative effects in some individuals.
- This vital system is currently at the center of renewed international research and drug development.
- Your doctor can also recommend certain products that align with your needs and help ensure you get the correct dosage.
- It’s essential to note that some CBD products may contain trace amounts of THC, and the quality and contents of CBD products can vary.
- THC is often administered by smoking marijuana, but it can also be found as an ingredient in capsules, edibles, tinctures, and oils.
We also must be mindful of “gimmick” products for which there is no reason to believe CBD is a meaningful addition. A 2013 report published in Neuropsychopharmacology described the case of a 19-year-old woman who had cannabis withdrawal symptoms. is cannabidiol addictive After being treated with CBD for 10 days, she experienced an effective decrease in the severity of her symptoms [1]. All these interactions seem promising when it comes to easing withdrawal symptoms and reducing the risk of addiction.
Included animal studies
If you think you might have an addiction to THC, talk to your doctor about available treatments. Treatments typically involve psychotherapy, although medications may sometimes be prescribed to treat co-occurring mental health conditions such as anxiety or depression. Some evidence suggests that the combined effects of CBD and THC may be dependent on dose. A 2019 study, for example, found that low doses of CBD actually played a role in amplifying the psychoactive effects of THC, while high doses of CBD reduced THC’s effects. Cannabis contains over 400 chemical compounds such as cannabinoids, terpenoids, flavinoids, and omega fatty acids.
- People taking high doses of CBD may show abnormalities in liver-related blood tests.
- The FDA approved Epidiolex for treating rare forms of epilepsy, including Dravet syndrome and Lennox-Gastuaut syndrome.
- An earlier study conducted in 2010 tested 94 cannabis users to evaluate the role of THC/CBD ratios in modulating the effects of psychoactive compounds and attentional bias to drug stimuli [2].
- Unlike hemp-extracted CBD, marijuana-derived CBD oil often contains levels of THC that exceed the federal 0.3% limit.
Clonazepam reduced blood pressure or heart rate, but CBD had no physical effects. They were told to use the inhaler whenever they felt the urge to smoke, to assess daily cigarette and inhaler use, and to monitor their craving once daily for 1 week. The results showed a significant reduction in the number of cigarettes smoked (≈40%) in the CBD inhaler group during the week of treatment, with a trend indicating a reduction after follow-up. Both groups also showed a reduction in cravings between day 1 and day 7, though not between day 1 and follow-up. Some CBD products may contain THC, the psychoactive compound found in marijuana. It’s essential to be aware of this possibility when purchasing CBD oil or other products.
Differences between CBD, Marijuana, Cannabis, and Hemp
They’re also legal on a federal level; you can easily find CBD oils online and over the counter in dispensaries, vape stores, wellness centers, and major pharmacies. People use CBD to manage their daily stresses by reducing anxiety, but reports from CBD users and preclinical studies suggest that CBD oil has remarkable medicinal potential. That said, preliminary research on CBD and its benefits are promising in relation to helping with mild to moderate health concerns and it is generally considered a safe substance. Health professionals do not consider CBD a cure-all for serious medical issues, including cancer.
